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mariomjr1/README.md

Hi there! I'm Mario Murakami, MD

I'm a Postdoctoral Research Fellow at the Martinos Center for Biomedical Imaging (MGH) & Harvard Medical School, bridging the gap between clinical neuroscience and computational analysis. With a background as a Medical Doctor (MD), my passion lies in using neuroimaging techniques and software development to understand the brain and explore solutions for neurological and psychiatric conditions.


About Me

  • MD from University of Sao Paulo with expertise in neuroanatomy and clinical research principles.
  • Focused on multimodal neuroimaging: fMRI (task-based & resting-state), PET-MR (neuroinflammation, receptor mapping), DTI (tractography, structural connectivity), and MRS (metabolite analysis).
  • Developing and applying computational pipelines for neuroimaging data analysis.

Tech Stack & Tools

  • Languages: Python, MATLAB and Shell Scripting
  • Python Ecosystem:
    • Neuroimaging: nibabel, nilearn, nipype
    • Data Science: Pandas, NumPy, SciPy, Scikit-learn
    • Visualization: Matplotlib, Seaborn, Plotly
    • Machine Learning: (Learning PyTorch, TensorFlow)
    • Graph Analysis: NetworkX (Learning StellarGraph, PyTorch Geometric)
  • Neuroimaging Software: FreeSurfer, FSL (FEAT, TBSS, etc.), SPM12, CAT12, CONN Toolbox, MRtrix3, AFNI, ANTS, Lead-DBS, TrackVis
  • Data Formats: DICOM, NIfTI, BIDS
  • DevOps & Workflow: Git, Docker, Singularity, High-Performance Computing (HPC) environments
  • Other: 3D Data Manipulation & Visualization

Current Research & Interests

My primary goal is to integrate multimodal neuroimaging data to build comprehensive models of brain structure, function, and metabolism. Currently exploring:

  • Mechanisms of neuroinflammation in conditions like Long-COVID using PET-MR (e.g., [11C]PBR28) and MRS.
  • Brain plasticity and inflammation following Spinal Cord Injury (SCI) using rsfMRI, PET-MR, and advanced dMRI (Connectome 2.0).
  • Developing robust, reproducible analysis pipelines for longitudinal and multi-site neuroimaging studies.
  • The application of graph theory and network neuroscience to understand connectome alterations.

Learning & Future Directions

I'm continuously expanding my skillset, currently diving deeper into:

  • Advanced Machine Learning techniques for neuroimaging (CNNs, GCNs).
  • Graph Convolutional Networks for analyzing brain connectivity data.
  • Transformer models and attention mechanisms applied to neurological time-series or imaging data.

Get In Touch


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  1. physioparse physioparse Public

    A physiological data processing pipeline for MRI research sessions. Aligns a continuous LabChart recording (RESP, RPIEZO, STIMTRIG, MRTRIG) to individual MRI sequences using MR-trigger–anchored pse…

    Python

  2. csf_velocity csf_velocity Public

    A five-step pipeline for measuring cerebrospinal fluid (CSF) velocity from phase-contrast fMRI data, with a graphical interface modelled on the Pseudotime Pipeline.

    Python

  3. flow_groups flow_groups Public

    Python