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C library for high-throughput sequencing data formats

Parse, view, query, edit, and export IFC, IDS, BCF, pointclouds and more AEC stuff. In the browser, server or desktop.

Open, self-hosted, IFC-native AEC platform: web BIM viewer + modeling, a ~100-module GC portal (RFIs, pay apps, CPM, construction accounting — double-entry GL/WIP → QuickBooks, e-sign), AI assist, IDS authoring, estimating + embodied carbon, a development proforma, and operate/dispose (CMMS, facility condition, rent roll, waterfall).

A DNA Sequence Alignment/Map (SAM) library for Clojure

Python toolkit for fast genotype I/O, ancestry analysis, population-genetics statistics, genotype QC, GWAS, and visualization

Query sequence data (VCF/BCF1/BCF2, Tabix, BGEN, PLINK) in R

OpenProject Add-in for Autodesk Revit

A fast and flexible program to annotate/interpret genetic variants in VCF/BCF file

MCP server for authoring IFC5/IFCX building information models through AI assistants. Supports spatial structures, geometry, materials, classifications, validation, glTF/Three.js preview, and multiple IFCX export formats.

Make Pseudo-Reference Genome from VCF/BCF

Read and write VCF and BCF files

HTSlib bindings for Crystal

HTSlib bindings for Ruby

A .NET library and a command line utility for converting BCF (Building Collaboration Format) files into json and vice versa.

R Bindings for htslib/bcf

BioC++ Input/Output library

This project is a BCF server implementation based on the BCF API using Node.js and MongoDB. It aims to quickly provide small servers to test the connection to BCF servers with other applications.

Navisworks Plugin to Read BCF files and convert BCF Topics in Navisworks Viewpoints

Quickly and accurately determine the pitch and volume of a sound sample.