Data analysis for the manuscript, "Site- and cell-type-specific miRNA and mRNA genes and networks across the cortex, striatum, and hypothalamus", Zacharias et al., Comm Biol, 2025
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Updated
Jun 5, 2025 - R
Data analysis for the manuscript, "Site- and cell-type-specific miRNA and mRNA genes and networks across the cortex, striatum, and hypothalamus", Zacharias et al., Comm Biol, 2025
Data analysis for the manuscript, "Site- and cell-type-specific miRNA and mRNA genes and networks across the cortex, striatum, and hypothalamus", Zacharias et al., Comm Biol, 2025
T-cell receptor repertoire analysis figures for the manuscript: Intestinal macrophages modulate synucleinopathy along the gut–brain axis.
gHH: Generalised Hodgkin–Huxley Model
Thymus-derived myeloid education signatures (MES): single-cell + spatial transcriptomics pipeline mapping thymic immune programs to microglial tolerance positioning under glucocorticoid stress.
An integrated computational pipeline for CRISPR-Cas13a (SHERLOCK) malaria diagnostics and trans-kingdom neuro-immune mapping, linking PfK13-driven pathogen detection to microglial homeostatic (CX3CR1/Iba1) set-points and Gut-Brain Axis (GBA) dysregulation.
Modulo Bio is a San Diego, California biotechnology company reprogramming the neuroimmune system to overcome the world's toughest neurological diseases. The company develops therapeutics that target microglia, the brain's resident immune cells, by combining stem cell engineering, neurobiology, multiomics (CRISPR and single-cell techniques), and…
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