My personal website, served at https://cthoyt.com

Multi-source drug-target due-diligence: ranked gene list → per-gene dossier across UniProt, OpenTargets, PubMed + cross-lineage DE scan + composite re-ranking. Claude Code / OpenClaw / SkillsMP skill.

Retrieval of the disease association and evidence from the Open Targets Platform, annotation of the association evidence through Clinvar, Sequence Ontology and PanelApp APIs, and finally filter and prioritise the protective targets when they possess LoF.

Autonomous Target Prioritization System An AI-driven solution designed for defense applications to rank and prioritize battlefield targets based on multiple factors such as proximity, weapon type, movement, and threat level. This project demonstrates machine learning techniques for autonomous decision support in military scenarios.

Private equity deal screening platform for target prioritization, leverage capacity, valuation discipline, and IC memo generation.

Leakage-aware multi-evidence framework for predicting human gene druggability. Integrates 22 biological feature blocks, 8 druggability targets, and 440 Random Forest/XGBoost benchmark datasets for systematic therapeutic target prioritisation.

Open heterogeneous-GNN benchmark for knee osteoarthritis target prioritization with leakage-free splits, baselines, ablations, a FastAPI graph dashboard, and interpretable target rationales.